Nooflux Axon Review – Is This Memory Enhancing Supplement Any Good?

This review is medically reviewed or fact checked to ensure factually accurate information.

With strict editorial sourcing guidelines, we only link to reputable media sites, academic research institutions and, when research is available, medically peer-reviewed studies. Note that an extensive list with all used Sources is available at the end of the review.

The information in our reviews is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

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Our extensive Nooflux Axon review will analyze both the supplement and the company. We will review the core active ingredients, claimed benefits, potential side effects and warnings, effectiveness, company’s reputation, best price, and stores to buy it from.

During this Nooflux Axon review, we will also address some of the most frequently asked questions regarding this brain supplement.

What Is Axon?

Axon made by Nooflux is a brain support supplement designed to improve brain function, enhance memory, and boost concentration. The formula is a blend of nootropic ingredients, adaptogens, and plant-based vitamins.

Nooflux Axon does not contain caffeine, and according to the manufacturer, all the ingredients are clinically proven to support cognitive functions.

Who Makes It?

Axon is made by the US-based company Nooflux Labs LLC. According to the official website, Nooflux Labs was founded with the mission to inspire the mental state of flow by developing authentic products that support human development. 

Their current product line includes four dietary supplements: Nooflux Rest (improves sleep, supports a healthy circulatory rhythm, boosts energy), Nooflux Axon, Nooflux Flow (improves focus, mental clarity, and supports peak performance), and Nooflux Zen (optimize natural stress response, mood, and general wellness).

Do you want to know more about Nooflux’s products? Read our full Zen Review.

Nooflux Labs contact details:

  • Phone: (415) 935-3077
  • Address: 2590 Windmill Ln #324, Henderson, NV 89074, United States
  • Email: support@noofluxlabs.com
  • Website: noofluxlabs.com

Axon Ingredients

The following section of our Nooflux Axon review will focus on what’s actually inside the formulation, starting with some of the core ingredients and finishing with a detailed list of other active ingredients, as well as all inactive ingredients included in the formulation.

Axon contains the following active ingredients per serving:

  • Lion’s Mane extract (30% Beta-D-Glucans) 500 mg
  • Bacopa Monnieri extract (50% Bacopaside) 200 mg
  • Citicoline (CDP-Choline) 200 mg
  • Ginkgo Biloba extract (24% Glycosides) 120 mg
  • Huperzine A 1% 10 mg
  • Vitamin B6 (Pyridoxal-5-Phosphate) 10 mg
  • Vitamin B1 (Thiamine) 10 mg
  • Vitamin B12 (Methylcobalamin) 100 mcg


Inactive ingredients include hypromellose (vegetable capsule shell), rice bran, and rice content.

Lion’s Mane Health Benefits

Lion’s Mane (Hericium Erinaceus) is a variety of curative mushroom, used in Traditional Chinese medicine for centuries. Scientific examination reveals that Lion’s Mane contains various health-promoting compounds, including beta-glucan and antioxidants.

Advocates insist that Lion’s Mane can help with a variety of health problems, including anxiety, depression, Alzheimer’s disease, high cholesterol, Parkinson’s disease, inflammation, and ulcers. Besides, Lion’s Mane is said to protect against cancer, stimulate digestion, and strengthen the immune system.

Lion’s Mane contains BDNF, a protein described by the Harvard psychiatrist John Ratey as “Miracle-Gro for your brain.” BDNF is a potent protein that strengthens existing brain cells and stimulates the production of new ones. More accurately, when your body produces BDNF, it enables a series of genes that create brand new neurons and pathways. 

Elevated levels of BDNF can slow down the natural aging process, improve memory, enhance learning skills, and quickly rewire your brain.

BDNF also increases your brain’s neuroplasticity. If you are facing a stressful situation or when your neurons get damaged, BDNF protects them and helps your brain cells come back even stronger. 

What does Bacopa Monnieri Do?

Bacopa Monnieri (also known as Brahmi or Herb of Grace), is a staple plant in traditional Ayurvedic medicine. Brahmi grows in wet, tropical climates, and its capacity to flourish underwater makes it popular for aquarium use.

When we review Bacopa Monnieri, we examine it first as a memory enhancer because of the remarkable effect it has on memory function. However, Brahmi can be far more than just a herbal extract for memory support.

There is strong evidence that Bacopa supplementation also heightens focus, increases attention, promotes calmness, and reduces stress. Bacopa Monnieri is an adaptogen, so it will definitely help you overcome anxiety levels and resist stress.

Bacopa Monnieri is rich in antioxidants, compounds that aid protect against cell damage caused by potentially harmful molecules called free radicals. Clinical studies confirmed that damage caused by free radicals is linked to many chronic conditions, such as certain cancers, diabetes, and heart disease.

Bacopa Monnieri contains potent compounds that may have antioxidant effects. For instance, bacosides, the main active compounds in Bacopa Monnieri, have been demonstrated to inhibit fat molecules from reacting with free radicals and also offset these free radicals.

When fat molecules react with free radicals, they undergo a process named lipid peroxidation. This process is linked to several conditions, such as Parkinson’s disease, Alzheimer’s disease, and other neurodegenerative disorders.

Bacopa Monnieri may help prevent stress and anxiety. It’s considered an adaptogenic herb, meaning that it increases your body’s resistance to stress. Research suggests that Bacopa Monnieri helps reduce anxiety and stress by raising your mood and lowering levels of cortisol, a hormone that is associated with stress levels.

What Is Citicoline (CDP-Choline)?

While there are many citicoline benefits, the most commonly discussed are support against cognitive decline and memory enhancement. Because citicoline is a good source of choline (and thus acetylcholine), it is mostly known for this benefit. 

For example, one study of 24 elderly volunteers showed increased working memory with CDP-Choline supplements. Another clinical study validated the same findings with “verbal memory formation” over 2-3 months.

However, citicoline can be beneficial for far more than mere memory and cognition. In one novel study, CDP-Choline was used to increase focus and attention in healthy adult women. Another series of studies indicated that citicoline was the right anti-addictive agent against cocaine addiction.

Another significant benefit of CDP-Choline is bioavailability. Most choline prodrugs, such as soy lecithin or choline bitartrate, are poorly absorbed by the human body. In contrast, CDP-Choline is highly bioavailable so that you can avoid massive doses and inefficient supplementation.

Finally, much evidence suggests that citicoline can be incredibly neuroprotective as well. This component is most likely due to uridine by way of preserving “dopaminergic neurons” in studies of different toxins.

While citicoline is technically cholinergic, that interacts with learning ability and memory formation. It also has effects on concentration and stimulation.

Some individuals may also find that CDP-Choline is an excellent stimulant without the traditional anxiety-inducing options. For people sensitive in this way, that makes anxiety much more manageable.

For those who want a little bit more, sometimes it is beneficial to mix citicoline with stimulants like Armodafinil, Adrafinil, or Modafinil. A more straightforward bet is to connect with an essential nootropic combination like caffeine and L-theanine to avoid overstimulation.

Axon Review – Pros & Cons

Pros

  • Caffeine-free energy and mood booster;
  • Non-GMO and vegan;
  • 3rd Party tested;
  • Affordable for a nootropic;
  • Beautiful presentation website with lots of useful information regarding ingredients and clinical research.

Cons

  • Contains Huperzine A, a lab purified substance from a plant called Chinese club moss
  • Axon is part of the so-called “Infinity Stack Pack,” which also includes the nootropic Flow. Nooflux Labs recommends taking both products at once for the best results, which can almost double your monthly costs.

Nooflux Axon Side Effects

Nooflux Axon is advertised as safe when taken as recommended. Looking at the list of ingredients, we tend to agree with this claim. The formulation doesn’t contain that many ingredients, and we are shown the precise serving size of each of them (unlike the “proprietary blend”-using scammers out there).

The ingredients used in Nooflux Axon are all well-researched. They are all well-understood with dozens and dozens of clinical trials looking at how these ingredients affect cognitive function, as well as their safety. 

That being said, we need to raise some awareness regarding two ingredients used in this formulation: Huperzine A and Ginkgo Biloba.

Huperzine A is possibly safe in adults when taken for short periods (less than six months). Because Huperzine A is a lab-synthesized compound and not a natural herbal extract as many manufacturers and supplement review websites want you to believe, it may cause some mild to moderate adverse effects in some users. 

Common Huperzine A side effects may include: 

  • Nausea
  • Blurred vision
  • Slurred speech
  • Diarrhea
  • Vomiting
  • Dry mouth
  • Loss of appetite
  • Contraction
  • Constipation
  • Sweating
  • Fainting
  • Restlessness
  • Twitching of muscle fibers
  • Cramping
  • Inability to control urination
  • Increased saliva and urine
  • Dizziness
  • Insomnia
  • High blood pressure
  • Swelling
  • Slowed heart rate

The second “yellow” flag is raised by Ginkgo Biloba. Common side effects of Ginkgo Biloba may include:

  • Bleeding disorders
  • Contact dermatitis (topical use)
  • Nausea/vomiting
  • Palpitations
  • Allergic skin reactions
  • Dizziness
  • Impaired fertility
  • Seizures
  • Stomach upset
  • Constipation
  • Weakness
  • Diarrhea
  • Vertigo (rare)
  • Headache
  • Restlessness
  • Subdural hematoma
  • Case reports of spontaneous bleeding from iris (in the eye) when used with aspirin

How Much Does It Cost?

The list price for Nooflux Axon is $25.99 for a 60 capsule bottle (30 servings). You can also choose to buy the supplement with a “Subscribe & Save” option, which is a 15% discount on the list price.

Where To Buy Nooflux Axon?

You can buy Nooflux Axon directly from the official website or Amazon (multiple stores).

Customer Testimonials

OneBrainReviews Avatar

This is an excellent product. I usually take three capsules four times a week before I go to class. I’ve looked at several different products and finally found Axon. This supplement has […] Read the full comment


OneBrainReviews Avatar

I’m currently taking four courses this semester and working a full-time job. Even though I try to eat as healthy as I can, I still feel mentally drained by the end of the day. I’ve heard a lot about nootropics and decided to see if they could help. Axon was […] Read the full comment


OneBrainReviews Avatar

I will be rebuying this product. I’m on my third week of taking this supplement, and I genuinely notice a difference. I have seen […] Read the full comment

Similar Supplements

Before we conclude our Nooflux Axon review, let’s take a quick look over several other similar nootropics that might be good alternatives for those who are not convinced by this dietary supplement.

Neuro-Spark made by NutraChamps – This highly rated nootropic supplement was specially formulated to support focus, memory, clarity, and energy. The formula is built around several core ingredients, including Ginkgo Biloba, DMAE, Rhodiola Rosea, and St. John’s Wort.

Neuro-Spark claimed benefits include:

  • Fast-acting and long-term benefits;
  • Clinically proven ingredients;
  • Contains 11 premium brain-boosting ingredients;
  • Made in the US.

Brain Booster made by Vital Vitamins – This brain supplement is one of the highest-rated and best-selling dietary supplements available. The formula can be used by both men and women and contains proven ingredients such as DMAE, Ginkgo Biloba, Vitamin B12, and Bacopa Monnieri.

Brain Booster claimed benefits include:

  • Reduce fatigue and mental fogginess;
  • Improves mood and logical processing;
  • Premium-quality ingredients;
  • Lab-verified formulation;
  • Non-GMO.

Brain Support made by 1 Body – Combining powerful herbal ingredients, Brain Support is widely regarded as one of the best brain supplements out there. The mixture of Bacopa Monnieri, Phosphatidylserine, Alpha GPC, Lion’s Mane Extract, Ginkgo Biloba, Rhodiola Rosea, and Huperzine A may improve memory, learning, and focus.

Brain Support claimed benefits include:

  • Non-GMO, 100% vegetarian, GMP Certified, 3rd Party Tested formula;
  • Supports memory and cognition;
  • Excellent value at only $0.23 / count;
  • It contains clinically proven nootropic ingredients.

Our Bottom Line

Nooflux Axon is packed with several powerful nootropics and adaptogens that we’ve written about here at the OneBrainReviews. They’re all known to have plenty of science to support their use and excellent safety profiles.

However, Nooflux Axon is just one part of the Infinity Stack Pack, and for best results, it should be taken along Nooflux Flow.


Frequently Asked Questions

The recommended dose is two (2) capsules in the morning with a glass of water.

You can order Nooflux Axon online from the official website or Amazon (multiple stores).

Nooflux Axon is a nootropic supplement specially formulated to enhance memory, brain function, and boost concentration.

Pregnant or nursing women under the age of 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.

You can contact the Nooflux Labs customer support department by phone at (415) 935-3077 (Monday-Friday, 10 AM – 5 PM PST) or email at support@noofluxlabs.com.

No, Nooflux Axon is not recommended to individuals under the age of 18.

Axon reviews on Amazon, as of January 2021, are very positive, with 85% of the customers ranking this supplement with four (4) stars or higher. Out of 127 customer reviews, here’s how this supplement ranks: 5 star – 69%, 4 star – 16%, 3 star – 8%, 2 star – 4%, and 1 star – 4%.

Nooflux Axon contains the following active ingredients: Lion’s Mane extract (30% Beta-D-Glucans) 500 mg, Bacopa Monnieri extract (50% Bacopaside) 200 mg, Citicoline (CDP-Choline) 200 mg, Ginkgo Biloba extract (24% Glycosides) 120 mg, Huperzine A 1% 10 mg, Vitamin B6 (Pyridoxal-5-Phosphate) 10 mg, Vitamin B1 (Thiamine) 10 mg, and Vitamin B12 (Methylcobalamin) 100 mcg.



Sources

  • Shengjuan Jiang, Yuliang Wang, and Xiaolong Zhang – Comparative studies on extracts from Hericium Erinaceus by different polarity reagents to gain higher antioxidant activities. Published online on April 20, 2016. Retrieved on January 27, 2021. [Source]
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  • Mori K., Obara Y., Moriya T., Inatomi S., and Nakahata N. – Effects of Hericium Erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Published in February 2011. Retrieved on January 27, 2021. [Source]
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  • Calabrese C., Gregory W. L., Leo M., Kraemer D., Bone K., and Oken B. – Effects of a standardized Bacopa Monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial. Published in July 2006. Retrieved on January 27, 2021. [Source]
  • Russo A. and Borrelli F.- Bacopa Monnieri, a reputed nootropic plant: an overview. Published in April 2005. Retrieved on January 27, 2021. [Source]
  • Khansari N., Shakiba Y., and Mahmoudi M. – Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Published in January 2009. Retrieved on January 27, 2021. [Source]
  • Tamara Simpson, Matthew Pase, and Con Stough – Bacopa Monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain. Published online on August 27, 2015. Retrieved on January 27, 2021. [Source]
  • Sultana R., Pierluigi M., and Butterfield D. A. – Lipid peroxidation triggers neurodegeneration: a redox proteomics view into the Alzheimer disease brain. Published in September 2013. Retrieved on January 27, 2021. [Source]
  • Montine TJ, Neely M. D., Quinn J. F., Beal M. F., Markesbery W. R., Roberts L. J., and Morrow J. D. – Lipid peroxidation in aging brain and Alzheimer’s disease. Published on September 1, 2002. Retrieved on January 27, 2021. [Source]
  • Saini N., Singh D., and Sandhir R. – Neuroprotective effects of Bacopa Monnieri in the experimental model of dementia. Published in September 2012. Retrieved on January 27, 2021. [Source]
  • Rai D., Bhatia G., Palit G., Pal R., Singh S., and Singh H. K. – Adaptogenic effect of Bacopa Monnieri (Brahmi). Published in July 2003. Retrieved on January 27, 2021. [Source]
  • Citicoline – webmd.com. Retrieved on January 27, 2021. [Source]
  • Citicoline – rxlist.com. Retrieved on January 27, 2021. [Source]
  • CDP-choline. Examine.com. Retrieved on January 27, 2021. [Source]
  • Pawel Grieb – Neuroprotective Properties of Citicoline: Facts, Doubts, and Unresolved Issues. Published in 2014. Retrieved on January 27, 2021. [Source]
  • Nicholas D. Wignall and E. Sherwood Brown – Citicoline in Addictive Disorders: A Review of the Literature. Published online on July 20, 2014. Retrieved on January 27, 2021. [Source]
  • The Unique Benefits of Citicoline – Natural Medicine Journal. Retrieved on January 27, 2021. [Source]
  • Wayne M. Clark, Benjamin J. Williams, Kenneth A. Selzer, Richard M. Zweifler, LuAnn A. Sabounjian, and Richard E. Gammans – A Randomized Efficacy Trial of Citicoline in Patients With Acute Ischemic Stroke. Retrieved on January 27, 2021. [Source]
  • Huperzine A – webmd.com. Retrieved on January 27, 2021. [Source]
  • Ginkgo Biloba – rxlist.com. Retrieved on January 27, 2021. [Source]
  • Nooflux Axon Amazon store page. Retrieved on January 27, 2021. [Source]

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