Mind-Max Review: An Evidence-Based Analysis

This review is medically reviewed or fact checked to ensure factually accurate information.

With strict editorial sourcing guidelines, we only link to reputable media sites, academic research institutions and, when research is available, medically peer-reviewed studies. Note that an extensive list with all used Sources is available at the end of the review.

The information in our reviews is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.

No Comments

Mind-Max is a herbal dietary supplement for focus, energy, memory, and clarity. The formula is made by Nature’s Sunshine, an American supplement manufacturer known for its many all-natural, herb-based supplements.

The supplement is based on a relatively simple formula that includes a 1,100 mg proprietary blend of Magnesium L-Threonate (a highly absorbable magnesium form) and three popular herbal extracts – Gotu Kola, Ginkgo Biloba, and Bacopa Monnieri.

What is Mind-Max?

According to Nature’s Sunshine, the supplement is designed to support brain, memory, concentration, help with cognitive function, and improve circulation and oxygen to the brain.

Please read our full Mind-Max review below for an in-depth analysis of all the key features of this focus and energy supplement. 

Our in-depth review will provide you with helpful insights on the company behind the product, claimed benefits, who should take the supplement, core active ingredients, price per serving, customers’ take on the product, where to buy it from at discounted price, potential adverse effects, and our take on whether you should consider trying the product or not.

About Nature’s Sunshine

Founded in 1972 by Kristine and Gene Hughes, Nature’s Sunshine is a manufacturer and multi-level marketer (MLM) of dietary supplements, including minerals, vitamins, herbs, and personal care products. 

The company’s products are primarily sold to the consumer by independent distributors who receive fees based on sign-up bonuses and their sales and commissions based upon the sales of any distributors they may have recruited.

Nature’s Sunshine is based in Lehi, Utah, with a manufacturing facility in Spanish Fork, Utah. 

Some of its best-selling supplements include Chlorophyll Liquid ES, Nutri-Calm, Stress-J, AnxiousLess, Mind-Max, and HistaBlock.

How to contact Nature’s Sunshine:

  • Address: 2901 W Blue Grass Blvd., Lehi, UT 84043
  • Website: naturessunshine.com
  • Phone: 1 (800) 223-8225 Monday-Friday: 6:00 AM to 6:30 PM MST


Nature’s Sunshine Mind-Max contains the following active ingredients:

  • Magnesium 70 mg
  • Mind-Max Proprietary Blend [Magnesium L-Threonate (Magtein), Gotu Kola aerial parts (Centella Asiatica), Ginkgo Biloba leaf extract, and Bacopa Monnieri leaf extract] 1,100 mg

Other inactive ingredients include gelatin, water, cellulose (plant), and magnesium stearate (vegetable).

Health benefits

In this next part of our Nature’s Sunshine Mind-Max review, we will discuss some of the core ingredients in the formulation, analyzing how these ingredients can benefit your cognitive health.

Magnesium (70 mg)

Magnesium is one of the most abundant minerals in your body. It’s linked to more than 300 metabolic reactions essential for human health, including blood pressure regulation, energy production, muscle contraction, and nerve signal transmission.

Interestingly, low Magnesium levels are associated with various illnesses, such as mood disorders, type 2 diabetes, migraines, and heart disease.

Although Magnesium can be obtained from many whole foods like green leafy vegetables, seeds, legumes, and nuts, up to 60% of the people in the Western world don’t meet their Magnesium needs with diet alone.

Magnesium L-Threonate

Magnesium L-Threonate is the salt formed from combining Threonic Acid (a water-soluble substance derived from the metabolic breakdown of Vitamin C) and Magnesium.

This new form is better assimilated. Animal research notes that it may be the most efficient type for boosting brain cells’ magnesium concentrations.

Magnesium L-Threonate is frequently used for its inherent brain benefits and may help manage brain disorders, such as age-related memory loss and depression.

Gotu Kola

Gotu Kola (Centella Asiatica) is a perennial plant indigenous to Southeast Asia’s tropical wetlands, commonly used as juice, tea, or green leafy vegetables. 

Gotu Kola has a long history of use in Ayurvedic Medicine and Traditional Chinese Medicine. Alternative practitioners believe Gotu Kola to have antidiabetic, memory-enhancing, anti-inflammatory, antidepressant, and antimicrobial properties. 

Gotu Kola is a common ingredient in many brain supplements, and it is available in capsule, powder, tincture, and tablet formulations.

Today, Gotu Kola extracts can be found in many brain supplements, where it is used to support memory and treat stress and anxiety. Although data from research and clinical studies are mixed, there is evidence of some direct and indirect benefits.

For instance, a 2017 review of studies published in Scientific Reports found that Gotu Kola extracts may directly enhance cognition and improve memory. 

However, it seemed to increase attention and relieve stress and anxiety only within an hour of consumption.

Gotu Kola is believed to reduce anxiety by regulating neurotransmitters’ activity known as gamma-aminobutyric acid (GABA). Asiatic acid is the primary compound in Gotu Kola assumed to trigger this effect.

By influencing how the brain absorbs GABA, Gotu Kola may relieve anxiety without the sedative effect of traditional GABA agonist drugs like barbiturates and Ambien (Zolpidem). 

It may also play a role in treating chronic fatigue, insomnia, and depression.

Ginkgo Biloba

Ginkgo Biloba is an antioxidant-rich herb used to enhance brain health and treat various conditions. However, while Ginkgo Biloba seeds are regularly used for healing purposes in Traditional Chinese Medicine, most brain supplements use extracts of the plant’s leaves.

Clinical research showed that a Ginkgo Biloba extract might improve mental processing and support memory in healthy older adults when taken daily for six weeks.

Taking Ginkgo Biloba before a highly stressful task also decreases cortisol levels and reduces stress-related high blood pressure.

Bacopa Monnieri

Bacopa Monnieri is widely promoted to treat epilepsy, thyroid health, memory disorders, focus, attention, stress, and anxiety. However, not all of these benefits are supported by scientific evidence.

On the other hand, Ayurveda sees Bacopa Monnieri as having intellect-enhancing properties. Due to this, many people call Bacopa a “nootropic,” meaning it may support healthy brain and nervous system function.

Bacopa contains saponin compounds (known as bacosides), which may inhibit inflammation in the brain and support brain chemicals’ communication associated with memory, cognition, and learning.

A 3-months study in 46 healthy adults noted that taking 300 mg of Bacopa Monnieri daily significantly enhanced memory, learning rate, and the speed of visual processing information compared with the placebo treatment.

Researchers asserted that Bacopa Monnieri might improve cognition, but well-designed trials comparing the supplement to medication are needed to better understand this plant’s potential benefits.

In a 2016 study of 60 college students, scientists discovered that six weeks of twice-daily therapy with Bacopa Monnieri (at a dose of 300 mg per day) induced improvements in tests relating to cognitive function.


One bottle of Mind-Max (90 capsules / 30 servings) costs $47.30.  

A “Subscribe and Save” autoship program is available on Nature’s Sunshine’s official website. The program offers automatic deliveries (every 30, 60, 90, or 180 days), free shipping, and a 25% discount.

Where to buy Mind-Max?

You can buy Mind-Max from the official Nature’s Sunshine store or various online retailers such as Amazon, Walmart, or eBay.

Mind-Max review – Claimed benefits


  • Supports proper brain functions, concentration, attention, and memory
  • Contains non-GMO verified, vegan bacopa leaf
  • Features a proprietary blend of natural herbs carefully formulated to promote circulation and improve natural energy
  • Most claims are backed by clinical research
  • Stimulants-free supplement


  • The formula doesn’t stand out with anything special
  • Most of the formula is hidden behind a proprietary blend, making it impossible to know precisely the amounts of each used ingredient
  • At $39.00 per bottle, the product is quite expensive for such a basic herbal supplement

User reviews

It is tough to judge because there is not an instant change. I do seem to recall names and events quicker than I could before taking the capsules. I am going to continue taking. […] Read full review

I had high hopes for this as I am a huge fan of the brand. I didn’t notice any difference after taking these very expensive pills. […] Read full review

We have a significantly inattentive child. I had heard of this from another parent, so we tried it. My son was more alert, more conversational, and completed his school work with a less apparent effort from the first few days. He also appeared to have more energy and was less stressed. I’m menopausal and plan to try it myself. […] Read full review

Recommendations, adverse effects, and warnings

Given the ingredients available in Nature’s Sunshine Mind-Max, some individuals may experience mild to moderate adverse effects, typically due to their bodies adjusting to the supplement.

Mind-Max side effects may include:

  • Dizziness
  • Irritability
  • Nausea
  • Dry mouth
  • Bloating
  • Sweating
  • Weakness
  • Loss of appetite
  • Drowsiness
  • Fatigue
  • Muscle tension
  • Headaches
  • High blood pressure
  • Stomach cramps

This herbal supplement contains Ginkgo Biloba, Gotu Kola, and Bacopa Monnieri. The existing research indicates that herbal extracts are more likely to cause side effects and unwanted interactions with certain medications when continuously taken for more than 30-40 days. 

We strongly suggest cycling the product regularly, taking one week off every four weeks as a minimum. Longer breaks may be required after repeated cycles.

Pregnant mothers shouldn’t avoid Bacopa since there are no studies regarding the safety of this plant during pregnancy. Furthermore, animal studies suggest that Bacopa Monnieri may reduce fertility.

Nature’s Sunshine Mind-Max also contains Ginkgo Biloba, a plant that may interact with some prescriptions.


As a dietary supplement, take three (3) capsules before breakfast and three (3) capsules before bed.

Before using this product, it’s best to speak with your healthcare provider first to ensure its safety for you.

How Mind-Max compares to alternatives

Before we conclude our Mind-Max review, let’s take a quick look over several other focus and energy supplements that may represent good alternatives for those not convinced by this formulation’s benefits.

Energy + Focus made by Zhou Nutrition – This caffeine + L-Theanine supplement claims to offer long-lasting energy without the harsh side effects of other caffeinated products. 

It is also worth mentioning that all Zhou Nutrition products are made with high-quality ingredients in GMP facilities in the United States. The company also has a Utah lab where they test each batch of products for purity and potency.

Energy + Focus costs just under $19.00 for a 60-capsules bottle (60 servings at a recommended dose of just one capsule per day).

Neuro-Peak made by Zhou Nutrition – Neuro-Peak is one of the most popular and highly regarded nootropics available now. The formula combines the benefits of several potent ingredients such as Vitamin B12, Bacopa Monnieri, Rhodiola Rosea, and Ginkgo Biloba.

One bottle of Neuro-Peak costs $18.99 (30 servings at a recommended serving of one capsule daily).

neuroIgnite made by Havasu Nutrition – This is another popular nootropic supplement for clarity, focus, and memory. Its formula includes 130 mg of St. John’s Wort, 300 mg of Bacopa Monnieri, and 50 mg of DMAE, alongside other ingredients for cognitive support.

neuroIgnite is caffeine-free and is priced at about $21.00 for a 30-capsule bottle (30 servings at a recommended dose of one capsule per day).

Do we recommend Mind-Max?

Nature’s Sunshine initially launched Mind-Max in 1994, but the company reintroduced a more potent version of this formula – with Magnesium L-Threonate – about a decade ago. However, the new and improved formula also came with a much greater price per serving.

We like the Magnesium L-Threonate in Nature’s Sunshine Mind-Max, as it is one of the best forms of Magnesium available today. And Magnesium has many benefits for brain health and proper cognitive function.

The formula also contains several herbal extracts with some benefits for memory, attention, focus, clarity, stress, and anxiety. Still, we recommend cycling the supplement regularly because of how herbal extracts work, taking one week off every three weeks as a minimum.

Frequently Asked Questions

Mind-Max herbal supplement is designed to support brain, memory, concentration, help with cognitive function, and improve circulation and oxygen to the brain. The formula contains ingredients with proven benefits for brain health and mental support. Overall, Nature’s Sunshine Mind-Max is a solid brain supplement, especially for those looking for a natural, herb-based, nutritional supplement.

Mind-Max can be taken with a daily multivitamin or other dietary supplements. However, it contains several herbal extracts that may interact with ingredients in other nutritional supplements.

Mind-Max brain supplement is intended for people looking for a natural supplement for attention, memory, focus, stress relief, and mood support.

Pregnant or nursing mothers should consult a medical doctor before taking Mind-Max. The formula contains Bacopa Monnieri, an ingredient that hasn’t been studied for safety during pregnancy. Furthermore, animal studies suggest that Bacopa Monnieri may reduce fertility.

You can contact Nature’s Sunshine’s customer support service by calling at 1 (800) 223-8225 or through the “Contact Us” form available on the company’s official website.

If you are not completely satisfied, you may return the unused portion of a product for a full refund. Call Nature’s Sunshine’s customer support to set up your return shipment to return any damaged products.

Mind-Max supplement for focus and energy is made by the American company Nature’s Sunshine.


At OneBrainReviews, we only use primary references for our articles, including peer-reviewed medical journals or well-respected academic institutions.

  • Gerry K. Schwalfenberg and Stephen J. Genuis – The Importance of Magnesium in Clinical Healthcare. Published on September 28, 2017. Retrieved on May 26, 2021. [Source]
  • Uwe Gröber, Joachim Schmidt, and Klaus Kisters – Magnesium in Prevention and Therapy. Published on September 23, 2015. Retrieved on May 26, 2021. [Source]
  • Threonic acid – National Library of Medicine. Retrieved on May 26, 2021. [Source]
  • Carlos Zarate, Ronald S. Duman, Guosong Liu, Simone Sartori, Jorge Quiroz, and Harald Murck – New paradigms for treatment-resistant depression. Published in July 2013. Retrieved on May 26, 2021. [Source]
  • Gohil K. J., Patel J. A., and Gajjar A. K. – Pharmacological review on Centella Asiatica: A potential herbal cure-all. Retrieved on May 26, 2021. [Source]
  • P. Hashim – Centella Asiatica in food and beverage applications and its potential antioxidant and neuroprotective effect. Published in 2011. Retrieved on May 26, 2021. [Source]
  • Panupong Puttarak, Piyameth Dilokthornsakul, Surasak Saokaew, Teerapon Dhippayom, Chuenjid Kongkaew, Rosarin Sruamsiri, Anchalee Chuthaputti, and Nathorn Chaiyakunapruk – Effects of Centella Asiatica (L.) Urb. on cognitive function and mood-related outcomes: A Systematic Review and Meta-analysis. Published on September 6, 2017. Retrieved on May 26, 2021. [Source]
  • W. Wisden, X. Yu, and N. P. Franks – GABA Receptors and the Pharmacology of Sleep. Published on October 10, 2017. Retrieved on May 26, 2021. [Source]
  • Jaime M. Monti, David Warren Spence, Kenneth Buttoo, and Seithi Kurippu R. Pandi-Perumal – Zolpidem’s use for insomnia. Published in February 2017. Retrieved on May 26, 2021. [Source]
  • Nan Mei, Xiaoqing Guo, Zhen Ren, Daisuke Kobayashi, Keiji Wada, and Lei Guo – Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports. Published on February 21, 2017. Retrieved on May 26, 2021. [Source]
  • J. A. Mix and W. D. Crews Jr – An examination of the efficacy of Ginkgo biloba extract EGb761 on the neuropsychological functioning of cognitively intact older adults. Published in June 2000. Retrieved on May 26, 2021. [Source]
  • R. Kaschel – Specific memory effects of Ginkgo biloba extract EGb 761 in healthy middle-aged volunteers. Published on November 15, 2011. Retrieved on May 26, 2021. [Source]
  • D. Jezova, R. Duncko, M. Lassanova, M. Kriska, and F. Moncek – Reduction of rise in blood pressure and cortisol release during stress by Ginkgo biloba extract (EGb 761) in healthy volunteers. Published in September 2002. Retrieved on May 26, 2021. [Source]
  • A. Russo and F. Borrelli – Bacopa monnieri, a reputed nootropic plant: an overview. Published in April 2005. Retrieved on May 26, 2021. [Source]
  • Tamara Simpson, Matthew Pase, and Con Stough – Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain. Published on August 27, 2015. Retrieved on May 26, 2021. [Source]
  • C. Stough, J. Lloyd, J. Clarke, L. A. Downey, C. W. Hutchison, T. Rodgers, and P. J. Nathan – The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects. Published in August 2001. Retrieved on May 26, 2021. [Source]
  • Navneet Kumar, L. G. Abichandani, Vijay Thawani, K. J. Gharpure, M. U. R. Naidu, and G. Venkat Ramana – Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial. Published on October 10, 2016. Retrieved on May 26, 2021. [Source]
  • Chaudhari K. S., Tiwari N. R., Tiwari R. R., and Sharma R. S. – Neurocognitive Effect of Nootropic Drug Brahmi (Bacopa monnieri) in Alzheimer’s Disease. Published on May 12, 2017. Retrieved on May 26, 2021. [Source]

You May Also Like


Leave a Reply

Your email address will not be published. Required fields are marked *

Fill out this field
Fill out this field
Please enter a valid email address.
You need to agree with the terms to proceed

AmiN.O. Energy Review: An Evidence-Based Analysis
Mind Lab Pro Review: Is It Safe and Effective? A Detailed Look

Latest Reviews


Amino Acids


Fatty Acids



Send this to a friend