Life Extension Neuro-Mag Review – 10 Things You Should Know

This review is medically reviewed or fact checked to ensure factually accurate information.

With strict editorial sourcing guidelines, we only link to reputable media sites, academic research institutions and, when research is available, medically peer-reviewed studies. Note that an extensive list with all used Sources is available at the end of the review.

The information in our reviews is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice.


Neuro-Mag is one of the best-selling brain health supplements that is touted to deliver Magnesium L-threonate, a highly absorbable form of magnesium, to support youthful memory performance and overall cognitive health.

Cognitive impairment is a condition where a person experiences trouble remembering, concentrating, learning new things, or making decisions that impact their lives. According to the CDC, more than 16 million Americans are living with cognitive impairment. 

While there are numerous ways to restore your brain health, brain health supplements offer the best way to improve your cognitive function.

But, how good is this brain supplement? We will provide you with an extensive Neuro-Mag review, so peruse the article and find out more about it.


Neuro-Mag is a magnesium-based brain supplement that supports memory and cognitive function, explicitly targeting the aging brain and nervous system. According to the manufacturer, Life Extension, Neuro-Mag also supports bone and cardiovascular health and helps boost metabolism, mood, and energy.

Neuro-Mag is designed explicitly for aging individuals who want to prevent or treat mental function deterioration caused by aging. What’s more, this brain supplement is suitable for anyone who wants to improve their memory or cognitive function.


Neuro-Mag is manufactured by Life Extension, a leading company in anti-aging and preventive health since 1980. Life Extension is located in Fort Lauderdale, FL, United States, and is part of the global Scientific Research and Development Services Industry. 

Its mission is to help extend the healthy human lifespan by discovering methods to curb diseases and control aging. Apart from brain health supplements, Life Extension also offers digestion, heart health, weight loss, sports supplements.

Life Extension best selling products include Super Ubiquinol COQ10, Gamma E Mixed Tocopherols & Tocotrienols, Pregnenolone, BioActive Complete B Complex, and Super Selenium Complex.

Life Extension offers excellent customer service. The company’s support team can help you in English, Danish, German, Spanish, Italian, or French. 

Life Extension contact information:

  • Website:
  • Phone: 1-800-678-8989
  • Address: 3600 West Commercial Blvd, Ft. Lauderdale, FL 33309, US


Neuro-Mag contains the following active ingredients per serving (3 capsules):

  • Magnesium (from 2,000 mg Magtein magnesium L-threonate) 144 mg

Inactive ingredients include vegetable cellulose (capsule), microcrystalline cellulose, stearic acid, silica, and vegetable stearate.

Here’s a quick breakdown of the core ingredient.

Magnesium L-threonate (Magtein) – Threonic acid is a highly soluble compound obtained from the metabolic breakdown of Vitamin C. When this acid combines with magnesium, it forms a slat known as magnesium L-threonate. 

This compound is readily absorbed by the body. It is one of the most effective ways to ensure magnesium reaches your brain cells and other parts of the body. 

Several studies and clinical trials conducted over the past decades have concluded that Magnesium L-threonate boosts the density of synapses within the brain. This, in turn, results in improved memory and cognitive function. 

To put it simply, the magnesium provided by this ingredient reverses brain aging, and therefore, boosts mental health and cognitive function, especially in seniors.

Magnesium helps promote positivity, memory, sleep quality. It’s used by the body for digestive efficiency, healthy aging, to strengthen the immune system as an antioxidant, and to prevent calcium overload. This nutrient can help promote healthier well-being for those with Vitamin D deficiencies, weight challenges, kidney stones, or heart problems.

Taking magnesium may improve sleep quality by helping your mind and body relax. This relaxation enables you to fall asleep faster and may improve your sleep quality.

In a study in 46 older adults, those taking a magnesium supplement daily fell asleep faster. They also noticed decreased insomnia symptoms and improved sleep quality.

What’s more, several animal studies have observed that magnesium can improve melatonin production. Melatonin is a hormone that guides your body’s sleep-wake cycle.

Magnesium has also been shown to bind to gamma-aminobutyric (GABA) receptors. The hormone GABA helps calm down nerve activity, which may otherwise affect sleep.

Everything You Need to Know – Benefits

Nearly half of individuals aged above 60 in the developed world suffer from magnesium deficiency. Magnesium is an essential mineral needed for more than 300 biochemical reactions in the human body. 

In addition to supporting bone health, cardiovascular function, energy, and metabolism, researchers have now established that magnesium is also essential for optimal cognitive function. 

Unfortunately, it is tough for your body to maintain optimal magnesium levels in the brain, leading to a significant decline in brain health, especially in the older population.

Neuro-Mag claimed benefits include:

1) Enhances memory – As a mineral, magnesium is responsible for regulating your brain’s tiny electrical switches it uses to map memories. When you don’t get sufficient magnesium in your diet, this impacts your brain cells’ connections that makeup memory. 

Neuro-Mag contains the highly soluble magnesium L-threonate that effectively boosts magnesium levels in your brain, resulting in improved memory.

2) Supports youthful brain plasticity – When you learn something new, your brain reacts by creating new synaptic connections between neurons. 

These neural pathways help your mind to retain information, live events, skills, among other things. Your brain’s relative ability to achieve this is called plasticity. Optimal levels of magnesium in the brain significantly boost youthful plasticity.

3) Increases attention and focus – As earlier explained, magnesium is essential for optimal brain and nerve function. 

This also includes increased attention and focus. Magnesium with GABA receptors helps maintain optimal transmission of this calming neurotransmitter to ensure you remain calm, attentive, and focused at all times.

4) Enhances cognition – Also called thinking, cognition is the combined function of memory and plasticity. 

Boosting magnesium levels inside your brain goes a long way towards memory support. Increasing magnesium levels at the connection points between neurons not only support plasticity but also strengthens those connections.

Where To Buy Neuro-Mag?

You can purchase the supplement from either the company’s official website or trusted global marketplaces such as eBay, Walmart, GNC, or Amazon.

Neuro-Mag is available in three options:

  • 150-count bottle for $45.97
  • 90-count bottle for $26.94
  • 3.3 oz powder for $28.50

Neuro-Mag Review – Pros & Cons


  • It may enhance memory and cognitive function;
  • It may support overall brain health;
  • Neuro-Mag is made by a reputable company known for producing quality supplements;
  • Available as capsules or flavored powder;
  • It contains Magnesium L-threonate that can cross the blood-brain barrier for fast increased efficiency and better absorption;
  • Overwhelmingly positive reviews from real users;
  • Non-GMO certified.


  • More expensive compared to other magnesium-based supplements;
  • It may not work for everyone;

Customer Testimonials

I’m 72 years old. I have had neuropathy from diabetes for the last 6 years. My step-daughter, Stephanie, says a friend of hers uses this to help with her neuropathy. I said, “I’ll give it a try.” I currently was taking 500 mg of a cheap magnesium supplement I buy at local drug stores. I looked on Amazon and found a compound called “Neuro-Mag®” brand “Magnesium L-Threonate.” I ordered a bottle. 1 month supply. I start taking the 3 pills a day […] Read full review

This is my third brand of Magnesium Threonate and definitely the best. I am 64, still working. My job is very stressful and mentally and physically demanding. I observe better memory, much more mental and physical endurance […] Read full review

Research has shown that magnesium increases brain function and memory performance and is likely to help delay or avoid dementia. I am a 37-year-old technology professional at the peak of my game. I take Neuro-Mag not to address a deficiency but to help ensure I stay there for as long as possible. I’ve taken it for 2 months, and the best description of its effect is […] Read full review

Side Effects & Warnings

Magnesium is LIKELY SAFE for most users when taken by mouth as directed. Doses less than 350 mg daily are safe for most adults. 

In some people, magnesium may cause nausea, stomach upset, diarrhea, vomiting, and other adverse effects. 

When taken in substantial amounts (greater than 350 mg daily), magnesium is POSSIBLY UNSAFE. Large doses might cause too much magnesium to build up in the body, causing severe adverse effects, including low blood pressure, an irregular heartbeat, slowed breathing, and confusion.

Is Neuro-Mag Effective?

Compared to other brain health supplements out there that are magnesium-based, Neuro-Mag is relatively more effective. This is because it features magnesium L-threonate as its core ingredient, a highly soluble form of magnesium that is easily absorbed in your brain for enhanced youthful cognition and healthy neural function. 

When used appropriately and as recommended by the manufacturer, users usually start to experience improvements in their overall brain health after three weeks. However, significant changes are only possible after the completion of the recommended dosage.

Similar Products

As you might expect, Life Extension Neuro-Mag is not the only supplement using the unique form of magnesium Magtein. Similar dietary supplements are available, and some may represent promising alternatives to Neuro-Mag.

Magnesium L Threonate made by Double Woods Supplements – This is another top-rated and well-regarded Magtein supplement designed to support cognitive function, short term, long term & working memory, and improve sleep patterns. The product is made in the USA and tested two times for safety and purity. 

Each bottle contains 100 capsules (25 servings), and each capsule contains 500 mg of Magnesium L-Threonate.

Magtein made by NOW Foods – This is one of the best selling Magtein supplements. Averaging a 4.6 rating on Amazon (over 1,200 reviews), the supplement made by NOW Foods is available in bottles of 90 capsules each (30 servings), and each serving provides 2,000 mg of Magnesium L-Threonate

The supplement is also free of wheat, gluten, soy, milk, egg, fish, shellfish, and tree nut ingredients.

Read our extensive NOW Foods Magtein review here.

Magnesium L Threonate made by Teraputics – The supplement offered by Teraputics comes conveniently packed in a bottle with 100 capsules giving you a supply of this essential mineral for nearly one month. The formula is designed to improve memory, reduce brain fog, improve concentration, improve sleep, and promote calmness. 

Teraputics’ Magnesium L Threonate is formulated with non-GMO, natural ingredients in the USA. Additionally, each bottle of our magnesium supplement is checked by a third-party lab for purity and potency.

Our Final Take

The main ingredient in Neuro-Mag is the magical magnesium mineral. Magnesium plays a significant role in nearly every bodily process and is a cofactor in at least 300 biochemical reactions in the body. More importantly, magnesium plays a role in neuroplasticity. 

Neuroplasticity plays a crucial role in how well your brain ages, with a loss of plasticity resulting in a cognitive function loss. Recent research shows that increased neural cell magnesium levels can potentially boost synapse density as well as plasticity, enhancing overall brain health and cognitive function.

However, not all magnesium supplements will have an impact on brain health. Magnesium L-threonate is the ultimate option because it can cross the blood-barrier barrier to effectively boost magnesium levels in your brain. 

This is what makes Neuro-Mag a highly effective brain supplement. Even though it has some potential side effects, it is an excellent option for aging individuals looking to give their brainpower a significant boost.

Frequently Asked Questions

Neuro-Mag is available in capsule form. The recommended dose is three (3) capsules daily.

You can purchase Life Extension Neuro-Mag from either the company’s official website or trusted global marketplaces such as eBay, Walmart, GNC, or Amazon.

Neuro-Mag contains Magnesium L-threonate, a superior form of magnesium that can cross the blood-barrier barrier to effectively boost magnesium levels in your brain. This makes Neuro-Mag a more effective magnesium-based supplement.

Life Extension Neuro-Mag can be used by pregnant or nursing mothers. However, as with all dietary supplements, we recommend caution. We advise consulting with your healthcare provider before taking the product.

You can contact the Life Extension customer service department using the official company website’s contact form or by calling at 1-800-678-8989. The support team can help you in English, Danish, German, Spanish, Italian, or French.

Neuro-Mag is not intended for children or teenagers under 18.

Neuro-Mag reviews on Amazon, as of February 2021, are very positive, with 89% of the customers ranking this supplement with four (4) stars or higher. Out of 2,406 customer reviews, here’s how this mineral supplement ranks: 

  • 5 star – 77%
  • 4 star – 12%
  • 3 star – 6%
  • 2 star – 1%
  • 1 star – 3%


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2 Comments. Leave new

  • Buying Proxy
    March 14, 2023 8:44 am

    Can I just say what a relief to uncover someone who genuinely knows what they are talking about on the web. You certainly know how to bring an issue to light and make it important. More people must look at this and understand this side of the story. I was surprised that you are not more popular since you most certainly possess the gift.

    • OneBrain Reviews Panel Team
      March 17, 2023 2:05 pm

      Thanks for the feedback. We are building our team this year, hopefully, we can do better content.


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